Due to the always uncertain future of Futurama, there has been four designated series finales.
Futurama is an animated TV comedy based in the future. It started out on Fox and eventually moved to Comedy Central.
The show has been aired sporadically in the past, leading to a lot of confusing for both fans and the shows' writers. The show has had 4 episodes that were written with the intention of them being the finale.
In the first few seasons of the show, the time and day that it aired changed a few times, and on top of that, the new episodes were often shown at different times due to sports ending later than expected. All of this combined to make it hard to keep up with every new episode of the show.
Fox eventually decided to (unofficially) cancel the show in the middle of its fourth season. Comedy Central decide to pick it up in 2006, and decided to make new episodes instead of just airing reruns. They also created a film that was going to act as the shows finale.
It took until 2009 for Comedy Central to pick the show up for another season. At first it wasn't certain that all of the original voice actors would be a part of it, but eventually they were. The season premiere ended up being the networks highest-rated night in 2010 and its highest-rated Thursday primetime in the network's history.
The future of the series has always been uncertain which has led to the multiple finales. "The Devil's Hands Are Idle Playthings", "Into the Wild Green Yonder" and "Overclockwise" have all been written to serve as a final episode for the show. The episode "Meanwhile" currently stands as the show's official series finale.